Several options.

1. Home baked loan with multisig
2. P2p with firefish or other entity acting as a broker
3. Defi
4. Futures

Also note:
- you can insure the collateral with options
- if your other option was to sell the collateral anyway, it might be a good option. I prefer not to sell btc.
- selling btc can have tax implications, loan is tax free

Yes, there are risks, I go through them in great detail. So it's not irresponsible when I explain all the risks (and I mean all).